comparison of the salivary immu-noglobulin concentration levels between children with early childhood caries and caries-free children

Authors

ali bagherian

department of pediatric dentistry, dental school abdullah jafarzadeh

department of immunology mohsen rezaeian

department of epidemiology, medical school, rafsanjan university of medical sciences, rafsanjan, iran shima ahmadi

department of pediatric dentistry, dental school mohammad taghi rezaity

abstract

background: early childhood caries (ecc) is one of the most common chronic child-hood diseases. in spite of the global decrease in dental caries in the past decades, ecc has become a significant problem in many developing countries and also in a few indus-trialized nations. saliva as a host factor can play an important role in the process of den-tal caries. objective: the aim of this study was to compare siga and igg as saliva components between ecc and caries-free groups. methods: in this cross-sectional study, samples of unstimulated saliva of 90 children (45 in ecc group & 45 in caries-free group) were taken with scully method. then the concentration levels of siga and igg were measured with enzyme linked immunosorbent assay and single radial im-munodiffusion methods. results: mean concentration levels of salivary siga and igg were significantly higher among children with ecc (p

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Journal title:
iranian journal of immunology

جلد ۵، شماره ۴، صفحات ۲۱۷-۲۲۱

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